Ageing Proses
Abstract
Many research and theory was trying to express how that old process can happened. First, free radical theory explain that all normal metabolism process in body can produce small free radical in number as intermediate substance. ROS (species oxygen reactive) covering H2O2, OH and O2 normally were produced with existence of electron leak from enchaining the transfer of electron go to high potential oxygen and ROS was predicted to cause cumulative damage to lifetime. Second, decreasing energy theory showed that cell energy production process need at least four phase with five kinds of enzyme so that the physiology process of energy produce in normal condition. When there is a trouble of enzyme activity, hence will happened inhibiting of energy production in one of this phase. It will be caused that energy will not be produced at all. As a result, the life capacities of cell decrease, so that the cell response to existence of environmental change will be also decreased. Third, telomerase theory expresses that telomere (part of chromosome tip) each time happened cell cleavage will be loss of its shares. The normal cell unable to produce telomerase, hence this telomere cannot grow again. Predictably, that losing of this telomere have a relationship with ageing process. Through telomerase enzyme have been proved to regenerate telomere, so that ageing (in cell level) could be discontinued. But, this is meaningless for human being life forever. Because cell death is only representing just one of so much many process making someone become old.